佰樂博生物代理AntibodySystem，InVivoMAb Anti-Rat CD198/CCR8 Antibody (Iv0256)體內(nèi)中和抗體，活性抗體

鏈接：https://www.antibodysystem.com/product/21632.html

名稱：InVivoMAb Anti-Rat CD198/CCR8 Antibody (Iv0256)體內(nèi)中和抗體，活性抗體

別名：C-C motif chemokine receptor 8, Ccr8

貨號：VRE85601

宿主：Mouse

適用物種：Rat

存儲緩沖區(qū)：0.01M PBS, pH 7.4.

形式：Liquid

純度：>95%

克?。?/span>Monoclonal

同型：IgG2a, kappa

應(yīng)用：ELISA, Neutralization

內(nèi)毒素水平：Please contact with the lab for this information.

UniProt：D4ADE0

用途范圍：僅用于科研

儲存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

產(chǎn)品購買聯(lián)系方式：027-65279366 /18162686757

郵箱：biolab-reagents@atagenix.com

QQ：2663991332

參考文獻：

CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory. PMID: 35140181

Chemokine Receptor-Targeted Therapies: Special Case for CCR8. PMID: 35158783

Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody. PMID: 36352891

S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells. PMID: 37420296

Blocking CCL8-CCR8-Mediated Early Allograft Inflammation Improves Kidney Transplant Function. PMID: 35973731

CD4(+)CCR8(+) Tregs in ovarian cancer: a potential effector Tregs for immune regulation. PMID: 37950246

Oxamate enhances the efficacy of CAR-T therapy against glioblastoma via suppressing ectonucleotidases and CCR8 lactylation. PMID: 37770937

The impact of CCR8+ regulatory T cells on cytotoxic T cell function in human lung cancer. PMID: 35354899

TGF-beta-induced CCR8 promoted macrophage transdifferentiation into myofibroblast-like cells. PMID: 35377281

CCR8 is a new therapeutic target in cutaneous T-cell lymphomas. PMID: 35201316

Immunotherapy Targeting CCR8+ Regulatory T Cells Induces Antitumor Effects via Dramatic Changes to the Intratumor CD8+ T Cell Profile. PMID: 37350632

Cutting Edge: CCR8 Signaling Regulates IL-25- and IL-33-Responsive Skin Group 2 Innate Lymphoid Cell Migration and Function. PMID: 37921466

C(8)Mab-3: An Anti-Mouse CCR8 Monoclonal Antibody for Immunocytochemistry. PMID: 35377236

CCR8 Signaling via CCL1 Regulates Responses of Intestinal IFN-gamma Producing Innate Lymphoid CelIs and Protects From Experimental Colitis. PMID: 33613532

CCR8 blockade primes anti-tumor immunity through intratumoral regulatory T cells destabilization in muscle-invasive bladder cancer. PMID: 32367308

Role of chemokines in the crosstalk between tumor and tumor-associated macrophages. PMID: 36173487

The Chemokine Receptor CCR8 Is a Target of Chimeric Antigen T Cells for Treating T Cell Malignancies. PMID: 35693763