標題：Anti-Romiplostim (Nplate) ELISA Kit試劑盒 羅米司亭Nplate Romiplostim
名稱：Anti-Romiplostim (Nplate) ELISA Kit試劑盒(KAD76501) 羅米司亭Nplate (Romiplostim)
介紹：羅米司亭Nplate (Romiplostim)是一種血小板生成素(TPO)受體激動劑，模仿人體的天然TPO，旨在提升免疫性血小板減少癥(ITP)患者血小板計數(shù)。免疫性血小板減少癥(ITP)是—種罕見的、嚴重的自身免疫性疾病，特征為血液中血小板計數(shù)低(血小板減少癥)和血小板生成受損。
鏈接：https://www.antibodysystem.com/product/19006.html
產(chǎn)品購買聯(lián)系方式：027-65279366 /18162686757
郵箱：biolab-reagents@atagenix.com
QQ：2663991332
貨號：KAD76501
描述:This assay employs the quantitative sandwich enzyme immunoassay technique. A Romiplostim protein has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any Anti- Romiplostim antiobody present is bound by the immobilized Romiplostim protein. After washing away any unbound substances, a biotin-labeled Romiplostim protein is added to the wells. Following a wash to remove any unbound protein-biotin reagent, a streptavidin- horseradish peroxidase is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of antibody that anti-Romiplostim protein bound in the initial step.
穩(wěn)定性和儲存性：When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 10%. For unopened kits, all reagents are stored as shown on the label of the reagent bottle, please store the Standard, Detection A, Detection B, and Capture Plate at - 20 ℃, the rest reagents should be store at 4℃.
檢測方法：Colorimetric
精度Intra-Assay Precision (Precision within an assay): <12%
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays): <15%
Three samples of known concentration were tested in twenty separate assays to assess inter-assay precision.：
樣品類型:Plasma, Serum
檢測類型:Quantitative
注意:For Research Use Only.
別名：羅米司亭、Nplate、Romiplostim 、Romiplate
儲存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
參考文獻：
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A Review of Romiplostim Mechanism of Action and Clinical Applicability. PMID: 34079225
Romiplostim. PMID: 18974747
A multicenter study of romiplostim for chemotherapy-induced thrombocytopenia in solid tumors and hematologic malignancies. PMID: 32499239
Romiplostim in adults with newly diagnosed or persistent immune thrombocytopenia. PMID: 33249935
Efficacy and safety of romiplostim in refractory aplastic anaemia: a Phase II/III, multicentre, open-label study. PMID: 33152120
Adults with immune thrombocytopenia who switched to avatrombopag following prior treatment with eltrombopag or romiplostim: A multicentre US study. PMID: 35179784
Romiplostim: a review of its use in immune thrombocytopenia. PMID: 22316355
Romiplostim in children with newly diagnosed or persistent primary immune thrombocytopenia. PMID: 34308495
Romiplostim for the management of pediatric immune thrombocytopenia: drug development and current practice. PMID: 31239245
Romiplostim: a novel thrombopoiesis-stimulating agent. PMID: 19386944
Efficacy and quality of life of Romiplostim in adults and children with immune thrombocytopenia: A review. PMID: 36550870
Romiplostim use in pregnant women with immune thrombocytopenia. PMID: 36156812
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Romiplostim management of immune thrombocytopenic purpura. PMID: 19401474
Romiplostim drug presence in pregnancy and lactation. PMID: 36848631
Development of Romiplostim for Treatment of Primary Immune Thrombocytopenia From a Pharmacokinetic and Pharmacodynamic Perspective. PMID: 27056734
Romiplostim and eltrombopag for immune thrombocytopenia: methods for indirect comparison. PMID: 22980701
Romiplostim: a breakthrough treatment for the management of immune thrombocytopenic purpura. PMID: 19200304
Thrombopoietin receptor agonists: ten years later. PMID: 31073079
Experts' review: the emerging roles of romiplostim in immune thrombocytopenia (ITP). PMID: 34313512
Use of Romiplostim during pregnancy as a rescue therapy in primary immune thrombocytopenia: Literature review and case description. PMID: 31116059
Romiplostim for the treatment of chronic immune or idiopathic thrombocytopenic purpura: a single technology appraisal. PMID: 19804691
Development of romiplostim: a novel engineered peptibody. PMID: 25578414
Romiplostim for SARS-CoV-2 Vaccine Induced Immune Thrombocytopenia. PMID: 34757966
Romiplostim: a second-generation thrombopoietin agonist. PMID: 19436840
Romiplostim for the management of perioperative thrombocytopenia. PMID: 29767837
Immune Thrombocytopenia in a Kidney Transplant Recipient Treated with Romiplostim. PMID: 35033295
Romiplostim-induced myelofibrosis. PMID: 24175353
Clinical overview and practical considerations for optimizing romiplostim therapy in patients with immune thrombocytopenia. PMID: 33781612
Thrombopoietin Receptor Agonists: Eltrombopag and Romiplostim for the Treatment of Chronic Immune Thrombocytopenia Purpura. PMID: 30880797
Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies. PMID: 36050822
Safety of romiplostim administered immediately after cord-blood transplantation: a phase 1 trial. PMID: 37589942
The development of romiplostim for patients with immune thrombocytopenia. PMID: 21434943
A Review on Romiplostim Mechanism of Action and the Expressive Approach in E. coli. PMID: 38282441
Immunomodulation with romiplostim as a second-line strategy in primary immune thrombocytopenia: The iROM study. PMID: 37735543
Romiplostim for temozolomide-induced thrombocytopenia in glioblastoma: The PLATUM trial. PMID: 31586022
Romiplostim in aplastic anaemia - another tool in the armamentarium. PMID: 33152102
Eltrombopag versus romiplostim in treatment of children with persistent or chronic immune thrombocytopenia: a systematic review incorporating an indirect-comparison meta-analysis. PMID: 29330464
Thrombopoietin Receptor Agonists (TPO-RAs): Drug Class Considerations for Pharmacists. PMID: 34160821
Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim? PMID: 31214173
Spotlight on romiplostim in the treatment of children with chronic immune thrombocytopenia: design, development, and potential place in therapy. PMID: 28408804
Safety of romiplostim and eltrombopag for children with immune thrombocytopenia: a pharmacovigilance study of the FDA adverse event reporting system database. PMID: 36803342
Romiplostim for Primary Immune Thrombocytopenia in Routine Clinical Practice: Results from a Multicentre Observational Study in Germany. PMID: 34959233
An update on romiplostim for treatment of acute radiation syndrome. PMID: 35274632
Romiplostim-related myelofibrosis in refractory primary immune thrombocytopenia: A Case report. PMID: 31232923
Romiplostim (Nplate()) as an effective radiation countermeasure to improve survival and platelet recovery in mice. PMID: 31021662
Comparability of biosimilar romiplostim with originator: Protein characterization, animal pharmacodynamics and pharmacokinetics. PMID: 36871442
Development of romiplostim for the treatment of patients with chronic immune thrombocytopenia: from bench to bedside. PMID: 20298251
Successful treatment of refractory secondary immune thrombocytopenia (antiphospholipid antibody syndrome-associated) with the combination of rituximab and romiplostim at the cost of severe bone pain: A case report and review of literature. PMID: 32611269
Romiplostim as Adjunctive Treatment of Refractory Amegakaryocytic Immune Thrombocytopenia in a Dog. PMID: 33115689
Romiplostim for thrombocytopenia following allogeneic stem cell transplantation: A case series. PMID: 30030975
Romiplostim use for thrombocytopenia following allogeneic hematopoietic stem cell transplantation: a case series from a single center in Qatar. PMID: 37961987
Assessment of romiplostim immunogenicity in pediatric patients in clinical trials and in a global postmarketing registry. PMID: 34638135
Romiplostim treatment for children with immune thrombocytopenia: Results of an integrated database of five clinical trials. PMID: 32902132
Romiplostim in the management of the thrombocytopenic surgical patient. PMID: 26033367
Romiplostim for Immune Thrombocytopenia in Neuroblastoma Patients Receiving Chemotherapy. PMID: 29683946
Efficacy of romiplostim in treatment of thrombocytopenia in children with Wiskott-Aldrich syndrome. PMID: 33131064
Romiplostim for management of chemotherapy-induced thrombocytopenia. PMID: 24414994
Romiplostim for therapy-related thrombocytopenia in pediatric malignancies. PMID: 28150377
A Novel Use of Romiplostim for SARS-CoV-2-induced Thrombocytopenia. PMID: 33003146
Generic romiplostim for children with persistent or chronic immune thrombocytopenia: Experience from a tertiary care centre in North India. PMID: 35467751
Romiplostim is effective for eltrombopag-refractory aplastic anemia: results of a retrospective study. PMID: 32876852
Romiplostim dose-response in patients with myelodysplastic syndromes. PMID: 23171070
The burden of immune thrombocytopenia in adults: evaluation of the thrombopoietin receptor agonist romiplostim. PMID: 22533524
Romiplostim promotes platelet recovery in a mouse model of multicycle chemotherapy-induced thrombocytopenia. PMID: 25754671
Romiplostim in children with immune thrombocytopenia: a phase 3, randomised, double-blind, placebo-controlled study. PMID: 27103127
Romiplostim as early treatment for refractory primary immune thrombocytopenia. PMID: 24068656
Romiplostim in patients undergoing hematopoietic stem cell transplantation: results of a phase 1/2 multicenter trial. PMID: 31805185
Quality by Design in Downstream Process Development of Romiplostim. PMID: 36439274
Assessment of romiplostim immunogenicity in adult patients in clinical trials and in a global postmarketing registry. PMID: 32311075
High-dose romiplostim accelerates hematologic recovery in patients with aplastic anemia refractory to eltrombopag. PMID: 32616921
[Pharmacological and clinical profile of romiplostim (Romiplate() 250 g for s.c. injection)]. PMID: 21747207
Romiplostim as a Therapeutic Intervention for Tacrolimus-induced Immune Thrombocytopenia in a Pediatric Cardiac Transplant Patient. PMID: 33181586
Romiplostim Treatment in Adults with Immune Thrombocytopenia of Varying Duration and Severity. PMID: 26066765
Fate Determination Role of Erythropoietin and Romiplostim in the Lineage Commitment of Hematopoietic Progenitors. PMID: 35489782
Severe romiplostim-induced rebound thrombocytopenia after splenectomy for refractory ITP. PMID: 25325908
