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Research Grade Ulocuplumab ( 烏洛魯單抗 )
  • 品牌:AntibodySystem
  • 產(chǎn)地:France
  • 型號:100ug
  • 貨號:DHF39901
  • cas:1375830-34-4
  • 發(fā)布日期: 2022-10-18
  • 更新日期: 2024-10-25
產(chǎn)品詳請
產(chǎn)地 France
品牌 AntibodySystem
保存條件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -223°C long term.
貨號 DHF39901
用途 類似物,陽性對照抗體
應(yīng)用范圍 類似物,陽性對照抗體
抗原來源 Mammalian cells
保質(zhì)期 1 year
抗體名 Research Grade Ulocuplumab
是否單克隆
克隆性
靶點 BMS-936564
適應(yīng)物種 Human
形態(tài) Liquid
宿主
標記物 Unconjugate
包裝規(guī)格 100ug
亞型 IgG
標識物 Unconjugate
濃度 1mg/ml%
免疫原 Human
是否進口

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Description

Ulocuplumab (BMS-936564) is a first-in-class fully human IgG4 monoclonal anti-CXCR4 antibody that inhibits the binding of CXCR4 to CXCL12. The CXCR4/CXCL12 (SDF-1) axis has been known for many years as a critical regulator of tumor proliferation, cell, as well as migration into and out of the bone marrow.

Catalog No.

DHF39901

Host species

Homo sapiens

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.


Concentration

1.59 mg/ml

Purity

>95%

Clonality

Monoclonal

Isotype

IgG4-kappa


Applications

Research Grade Ulocuplumab Biosimilar

Target

Stromal cell-derived factor 1 receptor,LCR1,HM89,LPS-associated protein 3,LAP-3,CXC-R4,CXCR-4,SDF-1 receptor,CD184,NPYRL,LESTR,Fusin,FB22,C-X-C chemokine receptor type 4,CXCR4,Lipopolysaccharide-associated protein 3,Leukocyte-derived seven transmembrane domain receptor

Purification

Protein A or G purified from cell culture supernatant.

Endotoxin level

Please contact with the lab for this information.

Expression system

Mammalian cells

Accession

P61073

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Alternative Names

BMS-936564, MDX-1338, MDX1338,CAS: 1375830-34-4

Note

For research use only. Not suitable for clinical or therapeutic use.


Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.

AntibodySystem由具有30多年蛋白抗體開發(fā)經(jīng)驗的 創(chuàng)立于法國,專注于生命科學(xué)和生物制藥領(lǐng)域研究,總部位于法國斯特拉斯堡市。AntibodySystem自主開發(fā)了高效、高產(chǎn)的真核重組表達系統(tǒng),利用該系統(tǒng)生產(chǎn)了高質(zhì)量的重組蛋白、抗體產(chǎn)品。目前產(chǎn)品包括藥物靶點蛋白以及對照抗體藥物、Invivo功能性抗體、SAA系列流式抗體、PEG抗體、磷酸化抗體、抗小分子抗體、ADA抗體、PK&ADA ELISA試劑盒。


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