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Target

AICD-57,A4,Beta-CTF,Protease nexin-II,Gamma-CTF(50),ABPP,S-APP-beta,APP,Abeta40,Abeta42,AID(59),Amyloid intracellular domain 59,AID(57),S-APP-alpha,Gamma-CTF(59),Beta-secretase C-terminal fragment,Amyloid-beta precursor protein,Amyloid precursor protein,Beta-APP42,PreA4,Alzheimer disease amyloid protein,APPI,PN-II,AICD-59,Alpha-secretase C-terminal fragment,Amyloid-beta A4 protein,Amyloid intracellular domain 57,CVAP,Amyloid intracellular domain 50,Beta-APP40,AD1,Cerebral vascular amyloid peptide,AID(50),Alpha-CTF,Gamma-CTF(57),AICD-50

Description

Aducanumab (brand name: Aduhelm) is an amyloid beta-directed monoclonal antibody that targets amyloid beta in the brains of people with Alzheimer’s to reduce its buildup. Aducanumab is a monoclonal antibody (a protein that helps your immune system target other proteins), and it is designed to help your body remove something called amyloid beta from the brain. Amyloid beta is an important protein involved in the progression of Alzheimer’s disease. Aducanumab is given intravenously (infused through a vein) monthly. Aducanumab does not cure Alzheimer’s disease, but one (of two) large clinical studies suggests that aducanumab may slow the progression of the earliest symptoms of Alzheimer’s disease.

Catalog No.

DHC12504

Host species

Homo sapiens

Species reactivity

Human

Form

Liquid

Storage buffer

PBS buffer pH 7.5

Concentration

1mg/ml

Purity

>95%

Clonality

Monoclonal

Isotype

IgG1-kappa

Applications

Research Grade Aducanumab Biosimilar

Purification

Protein A or G purified from cell culture supernatant.

Endotoxin level

Please contact with the lab for this information.

Expression system

Mammalian cells

Accession

P05067

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Alternative Names

BART, BIIB-037, CAS: 1384260-65-4

Note

For research use only. Not suitable for clinical or therapeutic use.

Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.

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