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| 產(chǎn)地 | France |
| 品牌 | AntibodySystem |
| 貨號(hào) | RHF34001 |
| 保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -727°C long term. |
| 用途 | 僅用于科研 |
| 應(yīng)用范圍 | WB,IHC,ELISA |
| 抗原來(lái)源 | NA |
| CAS編號(hào) | |
| 保質(zhì)期 | 1 year |
| 抗體名 | Recombinant Anti-CD81 (005-C01) antibody |
| 是否單克隆 | 是 |
| 克隆性 | 是 |
| 靶點(diǎn) | |
| 適應(yīng)物種 | Human |
| 形態(tài) | Liquid |
| 宿主 | Human |
| 標(biāo)記物 | Unconjugate |
| 包裝規(guī)格 | 100ug |
| 純度 | 95%% |
| 亞型 | IgG1 |
| 標(biāo)識(shí)物 | Unconjugate |
| 濃度 | 1mg/ml% |
| 免疫原 | NA |
| 是否進(jìn)口 | 是 |
CD81 (TAPA-1, target of anti-proliferative antibody-1) is a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T cells. In muscles, CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus. Like members of the tetraspanin family that include CD9, CD37, CD53, CD63, and CD82, CD81 is a cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a cell surface glycoprotein that is known to complex with integrins. CD81 appears to promote muscle cell fusion and support myotube maintenance. CD81 associates with CD19, CD21, Leu 13, and integrins on cell membrane and acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. CD81 is also localized in the tumor-suppressor gene region and is a candidate gene for malignancies.
RHF34001
Human
WB:1:2000~1:8000, IHC:1:50~100, Elisa:1:4000~1:8000
Human
Liquid
PBS buffer PH7.5
1mg/ml
>95%
Monoclonal
IgG1
WB,IHC,ELISA
Protein A or G purified from cell culture supernatant.
Please contact with the lab for this information.
Mammalian cells
P60033
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
CD81 antigen,TSPAN28,Target of the antiproliferative antibody 1,Tspan-28,Tetraspanin-28,CD81,TAPA1,26 kDa cell surface protein TAPA-1,
Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.
AntibodySystem由具有30多年蛋白抗體開(kāi)發(fā)經(jīng)驗(yàn)的 創(chuàng)立于法國(guó),專(zhuān)注于生命科學(xué)和生物制藥領(lǐng)域研究,總部位于法國(guó)斯特拉斯堡市。AntibodySystem自主開(kāi)發(fā)了高效、高產(chǎn)的真核重組表達(dá)系統(tǒng),利用該系統(tǒng)生產(chǎn)了高質(zhì)量的重組蛋白、抗體產(chǎn)品。目前產(chǎn)品包括藥物靶點(diǎn)蛋白以及對(duì)照抗體藥物、Invivo功能性抗體、SAA系列流式抗體、PEG抗體、磷酸化抗體、抗小分子抗體、ADA抗體、PK&ADA ELISA試劑盒。
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