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| 產(chǎn)地 | France |
| 品牌 | AntibodySystem |
| 貨號 | RHC37601 |
| 保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -726°C long term. |
| 用途 | 僅用于科研 |
| 應(yīng)用范圍 | WB,IHC,ELISA |
| 抗原來源 | NA |
| CAS編號 | |
| 保質(zhì)期 | 1 year |
| 抗體名 | Recombinant Anti-CD63 antibody (MOF11) |
| 是否單克隆 | 是 |
| 克隆性 | 是 |
| 靶點 | |
| 適應(yīng)物種 | Human |
| 形態(tài) | Liquid |
| 宿主 | Human |
| 標記物 | Unconjugate |
| 包裝規(guī)格 | 100ug |
| 純度 | 95%% |
| 亞型 | IgG1 |
| 標識物 | Unconjugate |
| 濃度 | 1mg/ml% |
| 免疫原 | NA |
| 是否進口 | 是 |
CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells. CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40. Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.
RHC37601
Human
WB:1:2000~1:8000, IHC:1:50~100， Elisa:1:4000~1:8000
Human
Liquid
PBS buffer PH7.5
1mg/ml
>95%
Monoclonal
IgG1
WB,IHC,ELISA
Protein A or G purified from cell culture supernatant.
Please contact with the lab for this information.
Mammalian cells
P08962
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
Ocular melanoma-associated antigen,TSPAN30,CD63 antigen,LAMP-3,Tetraspanin-30,OMA81H,Lysosomal-associated membrane protein 3,Tspan-30,Granulophysin,MLA1,Melanoma-associated antigen ME491,CD63,
Aiming to develop the most reliable bioreagents, AntibodySystem SAS was founded in 2019 in France by a team of professionals from top industrial companies and research institutes. The collective scientific and technical experiences in our team have brought breaking throughs in multiple product developments, including recombinant antibodies, recombinant proteins, biosimilar, RUO ELISA kits and other related products. By working with talented researchers and technicians, AntibodySystem continues to upgrade product qualities and lower the overall cost, offering accountable and affordable solutions for biolabs all over the world. Since its establishment, AntibodySystem has built long term and stable collaborations with academia, pharmaceutical industry, biotech companies and research hospitals, supporting their R&D by AntibodySystem's bioreagents with excellent data accuracy and reproducibility.
AntibodySystem由具有30多年蛋白抗體開發(fā)經(jīng)驗的 創(chuàng)立于法國,專注于生命科學(xué)和生物制藥領(lǐng)域研究,總部位于法國斯特拉斯堡市。AntibodySystem自主開發(fā)了高效、高產(chǎn)的真核重組表達系統(tǒng),利用該系統(tǒng)生產(chǎn)了高質(zhì)量的重組蛋白、抗體產(chǎn)品。目前產(chǎn)品包括藥物靶點蛋白以及對照抗體藥物、Invivo功能性抗體、SAA系列流式抗體、PEG抗體、磷酸化抗體、抗小分子抗體、ADA抗體、PK&ADA ELISA試劑盒。
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